Mitochondria as the center of many diseases
Most physicians used to say that they have only little to do with mitochondria. But more and more well-documented evidence shows that every therapeutic worker comes daily into contact with diseases and syndromes, with mainly caused by small cell organelles. Examples are: allergies, autoimmune diseases, heart problems and more. However, if mitochondria can be treated, diseases can be treated much more successful than previously known. Finally, are better prospects for affected patients!
Mitochondria – the power plants of the cell
Mitochondria play a very significant role for every human being. They are present in almost body cells – in several copies, in some cell (cardiac muscle) even by thousand. In strongly unfolded inner membrane systems of mitochondria, the called inner respiration (respiratory chain) takes place. In addition, these small cell organelles generate the majority of energy that cells need produce the energy molecule ATP, which requires much the human being every day that half of daily calorie requirement is included in turnover of molecule! couple cartier 2303 replica under 90 dollar
But that’s not all, more metabolic processes take place exclusively in mitochondria. For example, the energy-yielding degradation of pyruvate produced from glucose, whose product (acetyl-coenzymeA) finally enters the citrate cycle, which in turn proceeds the mitochondria and proceeds in same way, runs away. In addition, the cell’s own fatty acid degradation is metabolic pathway of the mitochondria and also parts the detoxifying urea cycle of liver are located here. The formation of iron-sulfur centers for enzymes is particular achievement of mitochondria. Furthermore, these cell organelles function as additional calcium storage of the cell and are important for the many times life-saving induction of apoptosis in humans, send the malfunctioning and outdated cells in the so-called „programmed cell death“, thus keeping the organs healthy and intact. couple rolex replica with logo 74 percent off
Mitochondriopathies – hereditary disease and environmental pollution
A multitude of enormously important metabolic processes that take over these microscopic „granules“! Especially tasks that go far beyond the events in single cell which they sit. That is why mitochondrial dysfunction can huge impact on affected person. Such mitochondriopathies are known as hereditary diseases. The show early in childhood or adolescence and affect individual enzymes of mitochondria, which completely absent in patients. Depending on importance of enzymes, the affected are exposed to severe suffering. The treatment is purely symptom-oriented, which located in Department of Paediatrics.
But is new evidence that mitochondriopathies, can occur later in life. However, are not consequence for genetic defects, but the acquired malfunctions of mitochondrial biochemistry. Triggers are for example:
- Environmental pollution and exposure to chemicals (heavy metals in tooth material, solvents, etc.)
- mechanical trauma (especially cervical spine)
- multifactorial overloads of physical detoxification functions
These factors lead to unwanted subliminal chronic inflammatory diseases, whose release of radicals causes oxidative and nitrosative stress. The stress of body can usually work for long periods, are not recognized and not eliminated. This effects a nonspecific continuous bombardment with radicals on affected tissue. pilots watch replica panerai 40mm review
The mitochondria are particularly stressed
Mitochondria have peculiarity among organelles of body cells: the carry at own, mitochondrial genetic material, the mtDNA. Unfortunately, not have the exquisite repair mechanisms that protect core DNA from errors and the effects of damage. Normally, this not a problem, because the several copies in cell, which can support each other in emergency and supply energy to cell, even other mitochondrion fails. However, if radical bombardment of mtDNA occurs, has serious consequences for mitochondria, the damage immediately converts into functionless enzyme units. In addition, mitochondria multiply by constricting with random distribution of mitochondrial genomes. Damaged mtDNA can spread and cause major problems in cell. pvd watches replica cartier bag review
Another point of attack are enzymes predominantly in mitochondria with iron-sulfur center (especially the respiratory chain). These are extremely susceptible to nitrosative stress, the precipitate and thus paralyze the entire mitochondrion: The energy supply comes to standstill and – even more fatal – the oxygen consumption of cell organelle decreases, which fuels the oxidative stress. Many organelle and cell structures are attacked and chemically altered can no longer perform their tasks. This leads to ever-widening malfunctions and not good conclusion is mitochondrion. If this happens in uncontrolled manner, which is probable under the described false control, this burdens the cell with sudden outflow of calcium – fatal for actually finely regulated signal effect of ion. It breaks unmanageable chaos in tissue – the symptoms are no longer overlooked.
Many diseases – multiple causes
Of course, the processes described not take place in isolation just one cell. The initial stresses put on affected body in many – unpredictable – places. In the entire organism, conditions occur in long run, which show the scenario described in earlier or more advanced stages. Subliminal or massive inflammations are constantly present in body it tries to help and eliminate the affected organs and tissues. But the finely-tuned controls that normally control such defensive reactions are no longer working properly. wholesale replica watches cartier drive replica
Depending on where the „leaks“ hit the mitochondria and later the cells and tissues, the following diseases can occur:
- Autoimmune diseases
- multiple sclerosis
- heart problems
In this way, the common phenomenon of multimorbidity is explained: Many patients begin with few health problems but develop more and more diseases over time. This is especially common for people with allergies and patients with autoimmune diseases.
Most of time, the assisting therapists can only achieve a delay of the development, but mostly – and this is much worse for involved – the therapists have watch the process of decay helplessly while in progress. However, anyone who is able to focus their medicine on mitochondria has good opportunities to really help those patients. women watch replica patek philippe moonphase
A concept with many starting points: mitochondrial medicine opens up new treatment opportunities
A medicine for mitochondria – this new direction of therapeutic action has the great advantage of addressing the real causes of the disease. Of course, first and foremost is finding and switching off the triggering loads. But mitochondrial medicine can do more: By using:
- orthomolecular medicine
- targeted dietary changes
- intestinal treatments
- Detoxification and
- specially developed diagnostic and therapy techniques
Mitochondrial medicine can halt the destruction of other mitochondria and:
- support damaged cells and cell organelles during regeneration
- and promote the elimination of already irreversibly destroyed mitochondria.
On the long run, a good recovery of the patient is visible. Depending on the previous stage of the disease and the degree of destruction of the tissue, a significant improvement of the symptoms can be achieved.
Mitochondrial medicine is therefore a young and very remarkable medicine that can enrich and improve the future of therapeutic action in many ways.
Author: Dr. med. Rainer Mutschler
Dr. med. Rainer Mutschler (BioMedical Center, Speyer)
Specialist in General Medicine, Naturopathic Medicine, Regenerative Mitochondrial Medicine, Homeopathy, Manual Medicine, Acupuncture, Aviation Medicine.
Board of the Int. Society for Regenerative Mitochondrial Medicine e.V., founder and head of the university curriculum „Regenerative MitochondriaMedicine and Environmental Medicine“ in the Master program KMKW of the European University Viadrina Frankfurt / Oder
67346 Speyer / Rhineland Palatinate
Tel .: 06232-49910 60
Fax: 06232-49910 88